Fattest State In America 2025. Obesity has been linked to a multitude of health complications, including early death, type 2 diabetes, heart disease, cancer, and stroke, making it a key determinant of a state's overall health levels. State, with an obesity rate of 40.6%.

West virginia (41%), louisiana (40.1%) and oklahoma (40%) are the states with the fattest populations in the nation, laying claim to the highest proportion of adults with a body. Smartasset ranked 100 of the largest u.s.